Divigel (Estradiol)
Divigel (Estradiol)
Divigel® is a prescription medicine for the treatment of menopausal symptoms in women. This revolutionary gel contains Estradiol, a type of estrogen that replaces the body’s low estrogen levels, providing relief from a variety of menopausal symptoms such as hot flashes, vaginal dryness, irritation, and burning.
Why Choose Divigel (Estradiol)?
- Effective Relief: Significantly reduce the severity and frequency of hot flashes and other menopausal symptoms.
- Easy Application: Available in a convenient gel form, allowing for simple application and rapid absorption by the body.
- Customizable Dosage: Divigel® is available in several dosage strengths, allowing for tailored treatment approaches as suggested by healthcare providers.
- Proven Track Record: Healthcare providers and patients alike value its effectiveness and safety profile.
How to Use Divigel (Estradiol)?
- Designed for once-daily use.
- Apply the gel to clean, dry skin on the upper thighs, as instructed by your healthcare provider.
- The quick-drying composition allows for dressing soon after application.
- Do not use Divigel® on the face, breasts, or inflamed skin.
- To promote effective absorption, avoid putting lotions or sunscreen in the gel-applied region.
Important Safety Information about Divigel
- Divigel® is not appropriate for everyone. Before taking Divigel®, discuss your medical history with your doctor, particularly if you have a history of heart disease, blood clots, liver difficulties, or hormone-dependent malignancies.
- Divigel® should not be used if you are pregnant, planning a pregnancy, or breastfeeding.
- For complete safety information, please refer to the product brochure or speak with your healthcare professional.
Fact Table
| Facts | Details |
| Generic Name | Estradiol |
| Brand Name | Divigel |
| Classification | Estrogen Hormone Replacement |
| FDA Approval Date | June 2007 |
| Indications | – Treatment of moderate to severe menopausal vasomotor symptoms.- Treatment of vulvar and vaginal atrophy.- Treatment of hypoestrogenism due to hypogonadism, castration, or primary ovarian failure.- Prevention of postmenopausal osteoporosis. |
| Dosage Form | Topical gel |
| Mechanism of Action | Estradiol, the active form of estrogen, works by replacing estrogen that is not naturally produced by the ovaries. |
| Common Side Effects | – Headache- Breast pain- Nausea- Back pain- Abdominal pain- Upper respiratory infection- Vaginal yeast infection |
| Contraindications | – Known allergy to estradiol or any component of Divigel- Known or suspected estrogen-dependent neoplasia- Active deep vein thrombosis, pulmonary embolism, or a history of these conditions- Active or recent (within the past year) arterial thromboembolic disease (e.g., stroke, myocardial infarction)- Liver dysfunction or disease- Pregnancy |
| Special Considerations | – Should not be applied to the face, breasts, or irritated skin.- Avoid applying sunscreen or lotion to the application area before the gel has dried.- Discuss the use of vaginal products with your healthcare provider while using Divigel. |
| How Supplied | Gel in single-use packets (available in several dosages: 0.25 g, 0.5 g, 1.0 g, containing varying amounts of estradiol per packet). |
Common Side Effects
Like all medications, Divigel (Estradiol) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Headache
- Breast pain
- Nausea
- Back pain
- Abdominal pain
- Upper respiratory infection
- Vaginal yeast infection
If you experience any of these side effects or others, make sure to discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Divigel (Estradiol)?
You can order Divigel (Estradiol) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
