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Dabigatran Etexilate Mesylate
Dabigatran Etexilate Mesylate
Dabigatran Etexilate Mesylate is a prescription medication used to prevent and treat blood clots. As an anticoagulant, it helps reduce the risk of stroke and deep vein thrombosis (DVT) by inhibiting certain clotting proteins in the blood. Commonly prescribed to individuals with atrial fibrillation (AFib) or those at risk of thromboembolic events, Dabigatran offers a reliable solution for those seeking to manage clot-related conditions effectively.
Why Choose Dabigatran Etexilate Mesylate?
- Reduces Risk of Stroke: Helps lower the likelihood of stroke in patients with atrial fibrillation.
- Prevents Blood Clots: Effective in preventing blood clots after certain surgeries (e.g., hip or knee replacement) and in treating existing clots.
- Convenient Oral Medication: Administered in capsule form for ease of use, without the need for routine blood monitoring.
- Rapid Onset of Action: Begins working quickly, typically within a few hours after taking the first dose.
- Lower Bleeding Risk: Compared to other blood thinners, it offers a balanced profile of efficacy and safety with reduced risks of serious bleeding complications.
How to Use Dabigatran Etexilate Mesylate?
- Take as Prescribed: Follow your healthcare provider’s dosing instructions carefully to ensure optimal results.
- Swallow Capsules Whole: Do not chew, break, or open the capsules to maintain the integrity of the medication.
- Maintain Consistent Timing: Take your dose at the same time each day for the most effective results.
- Avoid Missed Doses: If you miss a dose, take it as soon as possible but skip it if it’s almost time for your next dose. Do not double up.
- Stay Hydrated: Drink plenty of water when taking this medication to aid absorption.
- Inform Healthcare Providers: Always tell your doctor, dentist, or other healthcare professionals that you’re using Dabigatran before any procedures.
Important Safety Information about Dabigatran Etexilate Mesylate
- Do Not Stop Abruptly: Stopping Dabigatran suddenly without medical advice can increase your risk of blood clots.
- Interaction Warnings: Avoid taking this medication with other blood thinners (unless directed) or non-steroidal anti-inflammatory drugs (NSAIDs), as this increases bleeding risk.
- Avoid Certain Activities: Activities that could cause injury or bruising should be done with caution while taking this anticoagulant.
Fact Table
| Facts | Details |
| Brand Name | Pradaxa (common brand name) |
| Generic Name | Dabigatran Etexilate Mesylate |
| Drug Class | Anticoagulant (Direct Thrombin Inhibitor) |
| Indications | – Prevention of stroke in patients with atrial fibrillation (AFib) – Treatment of deep vein thrombosis (DVT) – Treatment of pulmonary embolism (PE) – Prevention of recurrent DVT and PE |
| Dosage Forms | Capsules |
| Available Strengths | – 75 mg – 110 mg – 150 mg |
| Administration Route | Oral |
| Mechanism of Action | Directly inhibits thrombin, preventing the formation of blood clots |
| Onset of Action | Typically within 1-2 hours after ingestion |
| Common Dosage | – 150 mg twice daily for patients with non-valvular atrial fibrillation – 110 mg or 75 mg for patients with renal impairment |
| Food Interaction | Can be taken with or without food, but consistent timing is recommended |
| Drug Interactions | – Increased bleeding risk with NSAIDs, antiplatelets, or other anticoagulants – Potential interactions with certain antifungals, anticonvulsants, and antibiotics |
| Storage Conditions | Store at room temperature (20-25°C/68-77°F); keep in original packaging to protect from moisture |
| Common Side Effects | – Gastrointestinal discomfort (e.g., nausea, indigestion) – Bruising or minor bleeding – Fatigue |
| Special Precautions | – Monitor for signs of bleeding – Not recommended in patients with mechanical heart valves |
| Missed Dose | Take as soon as remembered, but skip if it’s near the time for the next scheduled dose |
Common Side Effects
Like all medications, Dabigatran Etexilate Mesylate can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Nausea
- Stomach upset.
- Bruising or Minor Bleeding
- Indigestion
- Fatigue
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Dabigatran Etexilate Mesylate?
You can order Dabigatran Etexilate Mesylate using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
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