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Collagenase Santyl (Collagenase)
Collagenase Santyl (Collagenase)
Collagenase Santyl is a topical enzyme treatment designed to promote the healing of chronic wounds and burns. It works by breaking down collagen in necrotic tissue, helping to prepare the wound bed for healing and allowing the body’s natural healing processes to take over.
Why Choose Collagenase Santyl (Collagenase)?
- Promotes Wound Healing: Accelerates the removal of dead tissue and promotes healthy granulation tissue formation.
- Reduces Infection Risk: Helps prevent infection by keeping the wound clean and free from necrotic tissue.
- Easy Application: Comes in a convenient gel form for easy and precise application to the wound area.
- Non-toxic to Healthy Tissue: Effectively targets necrotic tissue while sparing surrounding healthy tissue.
How to Use Collagenase Santyl (Collagenase)?
- Prepare the Wound: Clean the wound thoroughly with saline or an appropriate wound cleanser.
- Apply the Gel: Squeeze a small amount of Collagenase Santyl directly onto the wound bed, ensuring full coverage of the necrotic tissue.
- Cover the Wound: Dress the wound with a suitable secondary dressing to protect it from contaminants.
- Change Dressings: Change the dressing as directed by your healthcare provider, usually once daily or as needed.
- Monitor Progress: Regularly check the wound for signs of improvement or any adverse reactions.
Important Safety Information about Collagenase Santyl
- For External Use Only: Collagenase Santyl is intended for topical application only. Avoid contact with eyes, mucous membranes, and intact skin.
- Contraindications: Do not use on patients with known hypersensitivity to collagenase or any other components of the formulation. Avoid use on wounds with significant bleeding.
- Not for Deep Wounds: Not recommended for use in deep or puncture wounds, animal bites, or surgical wounds unless directed by a healthcare professional.
- Store Properly: Keep the product stored at room temperature, away from direct sunlight and moisture.
Fact Table
| Facts | Details |
| Generic Name | Collagenase |
| Brand Name | Collagenase Santyl |
| Formulation | Topical gel |
| Indications | – Debridement of chronic wounds, Treatment of second-and third-degree burns |
| Mechanism of Action | Breaks down collagen in necrotic tissue, facilitating the removal of dead tissue and promoting healing. |
| Key Benefits | – Accelerates wound healing – Reduces infection risk – Easy application – Non-toxic to healthy tissue |
| Dosage and Administration | – Apply a thin layer directly to the wound bed once daily or as directed by a healthcare provider. – Cover with an appropriate secondary dressing. |
| Contraindications | – Hypersensitivity to collagenase or any component of the formulation.- Not to be used on wounds with significant bleeding. |
| Precautions | – For external use only. – Avoid contact with eyes and mucous membranes. – Consult a healthcare provider before use if pregnant or nursing. |
| Common Side Effects | – Local irritation (redness, swelling, burning sensation), Allergic reactions (rash, itching), Mild discomfort at the wound site |
| Storage Conditions | – Store at room temperature (20-25°C or 68-77°F), Protect from moisture and light. |
Common Side Effects
Like all medications, Collagenase Santyl (Collagenase) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Redness
- Swelling
- Burning sensation at the application site
- Wound Discomfort
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Collagenase Santyl (Collagenase)?
You can order Collagenase Santyl (Collagenase) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
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