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Clopixol Acuphase (Zuclopenthixol Acetate)
Clopixol Acuphase (Zuclopenthixol Acetate)
Clopixol Acuphase (Zuclopenthixol Acetate) is a trusted antipsychotic medication widely prescribed for short-term management of acute psychotic episodes, including schizophrenia and mania. It belongs to the thioxanthene class of medications and is formulated as a long-acting injection to provide rapid relief from distressing symptoms like hallucinations, delusions, and severe agitation.
Why Choose Clopixol Acuphase (Zuclopenthixol Acetate)?
- Fast Relief: Provides prompt symptom control for acute psychotic episodes.
- Long-Acting Formula: Reduces the need for frequent administration.
- Effective Symptom Management: Alleviates psychotic symptoms such as hallucinations and agitation.
- Improves Quality of Life: Helps stabilize mental health, promoting recovery and functionality.
How to Use Clopixol Acuphase (Zuclopenthixol Acetate)?
- Consultation: Always start with a thorough evaluation by your healthcare provider to determine if Clopixol Acuphase is right for you.
- Professional Administration: This injection must be administered by a healthcare professional, typically in a clinical setting.
- Follow-up Care: Regularly consult your healthcare provider for ongoing assessment and adjustments, if needed.
- Medication Adherence: Adhere to the prescribed treatment plan and avoid self-administration or dose modification.
Important Safety Information about Clopixol Acuphase
- Avoid Alcohol: Combining alcohol with this medication may increase side effects like drowsiness.
- Inform Your Doctor: Share your complete medical history, especially if you have liver problems, heart conditions, or are pregnant or breastfeeding.
- Monitor for Reactions: Be alert to any unusual physical or emotional changes and inform your healthcare provider immediately.
- Driving and Machinery: This medication may cause drowsiness; avoid tasks requiring full alertness until you know how it affects you.
Fact Table
| Facts | Details |
| Generic Name | Zuclopenthixol Acetate |
| Brand Name | Clopixol Acuphase |
| Drug Class | Typical Antipsychotic (Thioxanthene Derivative) |
| Indications | Acute psychosis, Mania, Agitation in schizophrenia, or related psychotic disorders |
| Dosage Form | Intramuscular injection |
| Strength | 50 mg/mL |
| Onset of Action | Within 2-4 hours |
| Duration of Action | 2-3 days |
| Mechanism of Action | Dopamine D1 and D2 receptor antagonist, leading to antipsychotic effects and sedation |
| Route of Administration | Intramuscular (IM) |
| Typical Dosage | 50-150 mg as a single dose, repeated every 2-3 days if necessary; maximum cumulative dose: 400 mg |
| Special Populations | – Elderly: Use with caution; lower initial dose may be required. – Pregnancy: Use only if necessary. – Breastfeeding: Excreted in breast milk, avoid use. |
| Common Side Effects | Sedation, dry mouth, constipation, orthostatic hypotension, weight gain, muscle rigidity |
| Contraindications | Hypersensitivity to zuclopenthixol or thioxanthenes, severe central nervous system depression, comatose states |
| Drug Interactions | – Alcohol: Increased sedation – CNS depressants: Enhanced effects – Antihypertensives: Potentiation of hypotension |
| Storage Conditions | Store below 25°C, protect from light |
Common Side Effects
Like all medications, Clopixol Acuphase (Zuclopenthixol Acetate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Drowsiness or sedation
- Dry mouth
- Muscle stiffness or tremors
- Weight gain
- Dizziness or low blood pressure
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Clopixol Acuphase (Zuclopenthixol Acetate)?
You can order Clopixol Acuphase (Zuclopenthixol Acetate) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
Frequently Asked Questions
- What is Clopixol used for?
- How does Clopixol work?
- What forms of Clopixol are available?
- How long does Clopixol stay in the body?
- Are there any side effects of Clopixol?
- Can I consume alcohol while on Clopixol?
- Are there any drugs or conditions that interact with Clopixol?
- Can Clopixol affect my ability to drive?
- What lifestyle adjustments should I consider while on Clopixol?
- What are the overdose symptoms of Clopixol?
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References
Clopixol [package insert]. Citywest Business Park, Citywest: Lundbeck (Ireland) Limited; 2020.
Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
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