Canada Post & FedEx shipping 
Cardene (Nicardipine Hydrochloride)
Cardene (Nicardipine Hydrochloride)
Cardene (Nicardipine Hydrochloride) is a prescription medication commonly used to manage high blood pressure (hypertension) and angina (chest pain). This calcium channel blocker works by relaxing and widening blood vessels, helping to improve blood flow and reduce strain on the heart.
Why Choose Cardene (Nicardipine Hydrochloride)?
- Effective Blood Pressure Management: Reduces hypertension to lower the risk of stroke, heart attack, and kidney problems.
- Improved Heart Health: Alleviates angina symptoms by enhancing oxygen supply to the heart.
- Quick Action: Especially effective for emergency settings when administered intravenously.
- Convenient Dosage Options: Available in sustained-release capsules for consistent blood pressure control.
How to Use Cardene (Nicardipine Hydrochloride)?
- Consult Your Healthcare Provider: Take Cardene only as prescribed by your doctor. Discuss your medical history and any other medications you’re taking.
- Follow Prescribed Dosage: Do not adjust your dose without consulting your physician. Overdosing or missing doses can impact treatment effectiveness.
- Monitor Blood Pressure Regularly: Keep track of your blood pressure to ensure the medication is working effectively.
- Avoid Certain Substances: Steer clear of alcohol and grapefruit products, which can interfere with the medication.
- Stay Consistent: Take the medication at the same time daily to maintain stable blood levels.
Important Safety Information about Cardene
- Not Suitable for Everyone: Inform your doctor if you have severe aortic stenosis, liver disease, or other chronic conditions.
- Pregnancy and Breastfeeding: Discuss potential risks if you are pregnant, planning to become pregnant, or breastfeeding.
- Drug Interactions: Avoid combining Cardene with other blood pressure medications, certain antibiotics, or antifungal drugs without a doctor’s approval.
- Allergic Reactions: Seek immediate medical attention if you experience symptoms such as rash, itching, or swelling.
Fact Table
| Facts | Details |
| Brand Name | Cardene |
| Generic Name | Nicardipine Hydrochloride |
| Drug Class | Calcium Channel Blocker (CCB) |
| Mechanism of Action | Inhibits calcium ion influx into cardiac and vascular smooth muscle cells, leading to vasodilation and reduced blood pressure. |
| Indications | – Hypertension (High Blood Pressure) – Chronic Stable Angina – Hypertensive Emergency (Intravenous form) |
| Dosage Forms | – Capsules (Oral) – Intravenous (IV) Solution |
| Strengths Available | – Capsules: 20 mg, 30 mg – IV Solution: 25 mg/10 mL (2.5 mg/mL) |
| Typical Dosage | – Oral: 20–40 mg three times daily (adjusted based on response) – IV: Initial infusion at 5 mg/hour, titrated up to 15 mg/hour as needed. |
| Administration Route | – Oral (Capsules) – Intravenous (IV Infusion) |
| Contraindications | – Severe aortic stenosis – Hypersensitivity to Nicardipine or any component of the formulation |
| Precautions | – Use with caution in patients with heart failure or hepatic impairment. – Monitor for hypotension or reflex tachycardia during administration. |
| Common Side Effects | – Headache – Flushing – Dizziness – Nausea – Edema (swelling in extremities) |
| Drug Interactions | – Beta-blockers: May enhance hypotensive effects. – CYP3A4 inhibitors/inducers: May alter nicardipine metabolism. – Digoxin: May increase digoxin levels. |
| Storage Instructions | – Capsules: Store at 20–25°C (68–77°F). – IV Solution: Protect from light; follow specific preparation and storage guidelines. |
Common Side Effects
Like all medications, Cardene (Nicardipine Hydrochloride) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Headache
- Dizziness or lightheadedness, especially when standing up
- Flushing (warmth or redness in the skin)
- Swelling in the ankles or feet
- Nausea
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Cardene (Nicardipine Hydrochloride)?
You can order Cardene (Nicardipine Hydrochloride) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
4 INSTALLMENTS, 6 WEEKS, 0% INTEREST
PharmaServe now offers you the option to make 4-interest-free payments by credit card once your order is confirmed using
Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
OZEMPIC: Huge price drop limited stock, limited time opportunity. 
MOUNJARO (12.5mg): Save up to 70% Use code MN12MG for an additional 10% off for 12.5mg. Chat now to order and save up to $90 or