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Alka-Seltzer (Acetylsalicylic Acid/ Citric Acid/ Sodium Bicarbonate)

Alka-Seltzer (Acetylsalicylic Acid/Citric Acid/Sodium Bicarbonate)

Alka-Seltzer (Acetylsalicylic Acid/ Citric Acid/ Sodium Bicarbonate)

Alka-Seltzer is a fast-acting over-the-counter remedy designed to relieve common digestive discomforts and minor aches. Its unique effervescent formula combines acetylsalicylic acid (aspirin), citric acid, and sodium bicarbonate. Together, they help reduce pain, neutralize stomach acid, and ease indigestion, providing quick and refreshing relief.

Why Choose Alka-Seltzer (Acetylsalicylic Acid/ Citric Acid/ Sodium Bicarbonate)?

  • Provides rapid relief from heartburn, acid indigestion, and upset stomach
  • Eases headaches, minor aches, and body pain
  • Effervescent tablets dissolve quickly for fast absorption
  • Convenient and easy-to-take alternative to regular pills
  • Trusted brand with decades of consumer use

How to Use Alka-Seltzer (Acetylsalicylic Acid/ Citric Acid/ Sodium Bicarbonate)?

  • Dissolve 2 tablets fully in a glass of water before drinking
  • Take as symptoms appear; do not exceed recommended dosage
  • Adults and children over 12 years: follow the dosage instructions on the package
  • Do not swallow tablets whole; always allow them to dissolve completely
  • Use only the amount directed; avoid prolonged use without medical advice

Important Safety Information about Alka-Seltzer

  • Do not use if you are allergic to aspirin or NSAIDs
  • Avoid use if you have a history of stomach ulcers, bleeding disorders, or severe liver/kidney disease
  • Not suitable for children or teenagers with viral infections due to the risk of Reye’s syndrome
  • Consult your doctor before use if you are pregnant, breastfeeding, or taking blood-thinning medications
  • Keep out of reach of children

Fact Table

 
Facts Details
Brand Name Alka-Seltzer
Generic Components Acetylsalicylic Acid (aspirin), Citric Acid, Sodium Bicarbonate
Drug Class Analgesic (acetylsalicylic acid), Antacid (sodium bicarbonate, citric acid)
Dosage Form Effervescent tablets
Administration Route Oral, dissolve tablets fully in water before drinking
Indications / Uses - Relief of heartburn, acid indigestion, and upset stomach - Headache relief - Minor aches and pains (muscle aches, backache, body pain) - Occasional hangover-related discomfort
Onset of Action Typically within 15–30 minutes after ingestion
Duration of Effect Around 4–6 hours, depending on individual response
Recommended Dosage Adults and children ≥12 years: 2 tablets dissolved in water every 4 hours as needed (Do not exceed 8 tablets in 24 hours)
Special Populations - Children/Teenagers: Avoid if recovering from viral infections (risk of Reye’s syndrome) - Pregnant Women: Use only under medical supervision (aspirin may affect fetal development) - Elderly: Increased risk of gastrointestinal bleeding
Contraindications - Allergy to aspirin, NSAIDs, or salicylates - History of stomach ulcers or gastrointestinal bleeding - Bleeding disorders (e.g., hemophilia) - Severe kidney or liver impairment - Asthma triggered by NSAIDs
Common Side Effects - Nausea - Heartburn - Upset stomach - Mild dizziness
Storage Conditions Store at room temperature in a dry place; keep tablets in original packaging to prevent moisture exposure
Availability Over-the-counter (OTC)

Common Side Effects

Like all medications, Alka-Seltzer (Acetylsalicylic Acid/ Citric Acid/ Sodium Bicarbonate) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
  • Mild stomach upset or nausea
  • Heartburn or acid reflux
  • Dizziness or lightheadedness
  • Allergic reactions (rare, but may include rash or breathing difficulty)
  • Ringing in the ears (tinnitus) if used in high doses
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Alka-Seltzer (Acetylsalicylic Acid/ Citric Acid/ Sodium Bicarbonate)?

You can order Alka-Seltzer (Acetylsalicylic Acid/ Citric Acid/ Sodium Bicarbonate) using these methods on our website:
  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills
Visit our How to order page.
Dr. Conor Sheehy, PharmD, BCPS

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.

Please note that due to government rules and regulations, orders may not exceed 3 months in supply.
Please call 1-800-258-0477 or email us if you have any questions or concerns.