Aggrenox (Dipyridamole / Acetylsalicylic Acid)

Aggrenox (Dipyridamole / Acetylsalicylic Acid)

Aggrenox combines the potency of Dipyridamole and Acetylsalicylic Acid (Aspirin) in a novel formulation intended to prevent stroke in those who have had a transient ischemia (mini-stroke) or a full ischemic stroke caused by thrombosis. Aggrenox reduces the likelihood of blood clots while boosting blood flow to the brain, providing a proactive approach to stroke prevention.

Why Choose Aggrenox (Dipyridamole / Acetylsalicylic Acid)?

• Dual-Action Formula: Aggrenox’s unique combination of Dipyridamole and Aspirin has a synergistic effect, giving greater protection against the formation of blood clots than either drug alone.
• Clinically Proven: Based on comprehensive clinical trials, Aggrenox has been shown to greatly lower the incidence of recurrent stroke.
• Convenient dosage: Aggrenox’s twice-daily dosage regimen is designed for ease of use and increased compliance.

How to Use Aggrenox (Dipyridamole / Acetylsalicylic Acid)?

• Take Aggrenox exactly as directed by your healthcare provider.
• Typically given twice per day, in the morning and evening, with or without meals.
• Swallow the capsule whole, without crushing or chewing.
• Consistent use at the same times throughout the day enhances effectiveness.

Important Safety Information about Aggrenox

• Before taking Aggrenox, let your doctor know if you have any allergies, or medical conditions, or are taking any other drugs, particularly blood thinners or NSAIDS.
• Individuals with a history of severe liver or renal illness, certain forms of cardiac disease, or recent bleeding disorders should avoid taking this medication.
• Aggrenox’s blood-thinning effects may raise the risk of bleeding. Exercise caution when participating in activities that could cause damage.
• Pregnant or nursing moms should consult their doctor before taking Aggrenox.

Fact Table

 

Facts	Details
Generic Name	Dipyridamole / Acetylsalicylic Acid
Brand Name	Aggrenox
Classification	Antiplatelet
Approved Uses	Primarily used to reduce the risk of stroke in patients who have had transient ischemia of the brain or a completed ischemic stroke due to thrombosis.
Mechanism of Action	Dipyridamole works by inhibiting the uptake of adenosine into erythrocytes and endothelial cells, leading to increased blood flow to the heart. Aspirin inhibits platelet aggregation by irreversibly inhibiting the COX-1 enzyme, thereby reducing the formation of thromboxane A2, a platelet activator.
Dosage Forms	Oral capsule
Common Dosages	25 mg/200 mg (Aspirin/Dipyridamole) twice daily
Side Effects	Headache, dizziness, abdominal pain, nausea, diarrhea, and bleeding are among the most common.
Key Warnings & Precautions	Increased risk of bleeding, especially in patients with peptic ulcer disease or those receiving anticoagulants. Patients with hypersensitivity to NSAIDs or salicylates should avoid use. Not recommended for patients with severe liver or kidney impairment.
Pregnancy Category	Category D (Evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, e.g., if the drug is needed in a life-threatening situation)
Interactions	Anticoagulants, NSAIDs, selective serotonin reuptake inhibitors (SSRIs), and other drugs that increase bleeding risk.
Alcohol Interaction	Alcohol may increase the risk of stomach bleeding.
Storage Instructions	Store at room temperature away from moisture and heat.
Pharmacokinetics	Dipyridamole: Peak plasma concentrations reached in about 2.5 hours. Aspirin: Rapidly absorbed, with a peak concentration in 15-20 minutes. Both components undergo hepatic metabolism.

Common Side Effects

Like all medications, Aggrenox (Dipyridamole / Acetylsalicylic Acid) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

• Headache
• Dizziness
• Abdominal pain
• Nausea
• Diarrhea
• Bleeding

If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Aggrenox (Dipyridamole / Acetylsalicylic Acid)?

You can order Aggrenox (Dipyridamole / Acetylsalicylic Acid) using these methods on our website:

1. Order Online
2. Order by Phone
3. Order by Fax
4. Order your refills

Visit our How to order page.