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Clarinex (Desloratadine)

  Clarinex (Desloratadine)

Clarinex (Desloratadine)

Clarinex (Desloratadine) is a prescription antihistamine used to relieve allergy symptoms such as runny nose, sneezing, watery eyes, and itching. It also helps reduce itching and hives caused by chronic skin reactions. Unlike many older antihistamines, Clarinex is non-drowsy for most people, making it a convenient choice for daily relief.

Why Choose Clarinex (Desloratadine)?

  • Provides effective relief from seasonal and year-round allergy symptoms.
  • Reduces sneezing, congestion, itchy or watery eyes, and runny nose.
  • Helps manage chronic hives and skin itching.
  • Non-drowsy for most users, so it can be taken during the day.
  • Works quickly and offers long-lasting 24-hour relief with once-daily dosing.

How to Use Clarinex (Desloratadine)?

  • Take Clarinex exactly as prescribed by your healthcare provider.
  • Usually taken once daily, with or without food.
  • Swallow tablets whole; do not crush or chew.
  • If using liquid form, measure the dose with a proper measuring device, not a household spoon.
  • Take the medication at the same time each day for best results.
  • Do not increase or decrease your dose without medical advice.

Important Safety Information about Clarinex

  • Inform your doctor if you have kidney or liver problems before starting Clarinex.
  • Avoid alcohol as it may increase the risk of drowsiness or side effects.
  • Consult your healthcare provider before taking with other medications or herbal supplements.
  • Use caution when driving or operating machinery until you know how the medicine affects you.
  • Not recommended for children under 6 months unless prescribed.
  • Pregnant or breastfeeding women should consult their doctor before use.

Fact Table

 
Facts Details
Generic Name Desloratadine
Brand Name Clarinex
Drug Class Antihistamine (Selective H1-receptor antagonist)
Indications / Uses - Relief of symptoms associated with seasonal allergic rhinitis (hay fever) - Relief of symptoms of perennial allergic rhinitis - Treatment of chronic idiopathic urticaria (hives)
Usual Adult Dose 5 mg once daily (tablet or ODT)
Pediatric Dose - 6–11 months: 1 mg once daily (2 mL oral solution) - 1–5 years: 1.25 mg once daily (2.5 mL oral solution or 1.25 mg ODT) - 6–11 years: 2.5 mg once daily (tablet or 5 mL oral solution) - ≥12 years: 5 mg once daily
Mechanism of Action Selectively blocks histamine H1 receptors to reduce allergic symptoms such as sneezing, runny nose, itchy/watery eyes, and hives.
Onset of Action Within 1 hour
Duration of Action Approximately 24 hours (once-daily dosing)
Contraindications - Known hypersensitivity to desloratadine or loratadine
Precautions - Severe renal impairment: use with caution - Consult doctor before use in pregnancy or breastfeeding
Common Side Effects - Headache - Dry mouth - Fatigue - Sore throat - Muscle pain
Drug Interactions - May interact with strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin) - Alcohol may increase drowsiness
Storage Store at room temperature (20°C to 25°C / 68°F to 77°F); protect from moisture and heat
Availability Prescription only (varies by country)

Common Side Effects

Like all medications, Clarinex (Desloratadine) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
  • Sore throat
  • Muscle pain
  • Fatigue or tiredness
  • Dry mouth
  • Menstrual cramps
  • Upset stomach
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Clarinex (Desloratadine)?

You can order Clarinex (Desloratadine) using these methods on our website:
  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills
Visit our How to order page.
Dr. Conor Sheehy, PharmD, BCPS

Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.

Please note that due to government rules and regulations, orders may not exceed 3 months in supply.
Please call 1-800-258-0477 or email us if you have any questions or concerns.