What organs does Eliquis affect?

What organs does Eliquis affect?

A widely prescribed anticoagulant medication, Eliquis (apixaban) is primarily used to prevent blood clots, significantly reducing the risk of stroke and systemic embolism in patients with conditions such as atrial fibrillation (AFib) and venous thromboembolism (VTE). While its main target is the cardiovascular system, preventing the formation of blood clots, the question of “What organs does Eliquis affect?” is pertinent, as its effects may extend to various organs throughout the patient’s body. It is crucial for those interested in taking Eliquis or who have already been prescribed this medication to understand the comprehensive impact it can have on organ function, ensuring they are well informed about the potential breadth of Eliquis’ effects on their health.

Understanding Eliquis and How it Works

As a direct oral anticoagulant (DOAC), Eliquis inhibits factor Xa, which is a crucial enzyme in the coagulation cascade. By blocking factor Xa, it prevents the conversion of prothrombin to thrombin, ultimately reducing the formation of blood clots in patients. This mechanism primarily targets the cardiovascular system but can also indirectly influence the function of other organs as well.

Impact on Vital Organs

If you are a patient concerned about what organs Eliquis affects, here is a rundown of the organs and systems that anticoagulants may affect. This will help you better understand how Eliquis affects the body’s different organs as well as give you peace of mind, knowing that this prescription medication will not be harmful to your health.

Cardiovascular System:

  • Eliquis primarily affects the patient’s cardiovascular system by preventing the formation of blood clots in the arteries and veins. By reducing the risk of clot formation, it can help prevent complications such as stroke, heart attack, as well as pulmonary embolism.
  • While it is highly effective in preventing thromboembolic events, this prescription medication does not directly affect the patient’s heart function or blood pressure regulation. However, Eliquis’ role in preventing cardiovascular events indirectly benefits overall heart health and function.


  • Eliquis is metabolized primarily in the liver by the cytochrome P450 enzyme system, specifically the CYP3A4 and CYP3A5 enzymes. Metabolism in the liver is an essential step in the breakdown and elimination of Eliquis from the body.
  • While Eliquis metabolism occurs in the liver, it generally does not have any significant impact on the patient’s liver function. However, there are also patients with pre-existing liver disease who may require dose adjustments or closer monitoring while taking the medication.


  • While the liver is the primary site of metabolism for Eliquis, a small portion of the medication is eliminated through the kidneys. However, renal excretion only plays a minor role in the overall clearance of Eliquis from the body.
  • Patients with impaired kidney function may require dose adjustments or closer monitoring while taking this medication to prevent drug accumulation in the body and its potential adverse effects.

Gastrointestinal Tract:

  • After metabolism in the liver, Eliquis and its metabolites are eliminated from the body primarily through the gastrointestinal tract via feces. This route of elimination contributes to the overall clearance of the medication from the body.
  • While Eliquis generally does not have any direct effects on gastrointestinal function there are still some patients who may experience gastrointestinal side effects such as nausea, vomiting, or diarrhea.

Hematological System:

  • Eliquis primarily targets the hematological system by inhibiting blood clot formation. By blocking factor Xa, it helps maintain the balance between coagulation and anticoagulation, thus reducing the risk of thromboembolic events in patients.
  • While Eliquis is very effective in preventing clot formation, it also increases the risk of bleeding. Patients who are taking the drug should be monitored regularly for any signs of bleeding complications, as well as dosage adjustments, which may be necessary based on individual patient factors.

While Eliquis primarily affects these organs and systems, it is essential to recognize that all medications may have systemic effects to patients to some degree. Patients who are taking Eliquis should be monitored regularly for any signs of adverse effects, which may include bleeding complications, changes in their liver function, and renal impairment. Additionally, those individuals with pre-existing liver or kidney disease may also require dose adjustments or closer monitoring while taking the medication.

As with any medication, patients should consult their healthcare provider for personalized guidance regarding the use and potential effects of Eliquis on their health. Regardless of whatever concerns you may have, having clear and open communication with your healthcare provider is the best way for you to get your concerns addressed.

Does Eliquis affect your organs?

Eliquis exerts its primary effects on the cardiovascular system by preventing blood clot formation and reducing the risk of stroke and systemic embolism in patients. However, it also interacts with the patient’s different vital organs such as the liver, kidneys, and gastrointestinal tract.

Understanding these interactions is very crucial for optimizing patient care and ensuring the safe and effective use of Eliquis in clinical practice. Healthcare providers should consider individual patient factors, including organ function and comorbidities when prescribing to their patients and monitor them closely for any potential adverse effects.

By addressing these considerations, healthcare providers will be able to help patients maximize the benefits of Eliquis while minimizing the risk of complications, ultimately improving patient outcomes and their overall quality of life.

Exploring Affordable Eliquis Options

In case you are interested to buy Eliquis or are still considering it as your anticoagulant, do not hesitate to contact us so we can promptly assist you with any concerns that you may have about Eliquis. 

In case you have been taking Eliquis already, feel free to share your experience with Eliquis therapy. How satisfied are you with the treatment so far? Is Eliquis treatment something you’d recommend to other patients? Or has it affected any of your organs or not? 

It is common knowledge that taking Eliquis can be quite costly, thus you must explore different options where you can purchase the prescription medications that you need. A reliable option for this is PharmaServe. Aside from having stock available of even the most in-demand prescription medications in the world, PharmaServe also ensures that it can provide these popular prescription medications at affordable prices. 

Get your medications online

PharmaServe is a trusted online pharmacy when it comes to affordably priced in-demand prescription medications. The website aims to support its patients by providing them with better-priced medications. Patients will also be able to purchase the prescription medications that they need without any hassle. In case customers need any assistance concerning any medications that the website is offering or if it is about their order, PharmaServe has a dedicated team of customer service representatives who will be able to assist and answer any queries 24/7.

Loyal customers of PharmaServe will also be delighted to know that the website offers a loyalty program wherein customers will receive rewards points every time they purchase their prescription medications through PharmaServe.

So do not worry about needing to buy Eliquis and not finding it in stock or finding it expensively priced, always check out PharmaServe to ensure that you are getting the best price for this popular prescription medication.

References and Further Reading





Interest-Free Payments


PharmaServe now offers you the option to make 4-interest-free payments by credit card once your order is confirmed using

EV SSL Encrypted

Stay informed and healthy! Sign up and never miss out on valuable health insights directly to your inbox

* indicates required