Dexilant is a medication used to reduce stomach acid and treat conditions like acid reflux and ulcers. While it can be effective for these conditions, it may also come with certain side effects. Here’s a breakdown of the possible side effects associated with Dexilant:
Serious Side Effects:

  • Vitamin B12 Deficiency: Dexilant reduces stomach acid, which is essential for proper absorption of Vitamin B12. If you have been taking Dexilant for an extended period (more than 3 years), discuss the possibility of Vitamin B12 deficiency with your doctor.
  • Low Magnesium Levels: Prolonged use of Dexilant (at least 3 months) can lead to low magnesium levels in some individuals. Symptoms of low magnesium may include seizures, dizziness, irregular heartbeat, jitteriness, muscle aches or weakness, and spasms in the hands, feet, or voice. If you experience these symptoms, immediately discuss it with your doctor.
  • Stomach Growths (Fundic Gland Polyps): Long-term use of proton pump inhibitor (PPI) medications like Dexilant is associated with an increased risk of developing fundic gland polyps in the stomach, particularly after using PPI medicines for more than a year.
  • Severe Skin Reactions: Although rare, Dexilant can cause severe skin reactions that may affect any part of the body. These reactions may include skin rash with blistering, peeling, or bleeding on various skin areas, including the lips, eyes, mouth, nose, genitals, hands, or feet. Additionally, you might experience symptoms such as fever, chills, body aches, shortness of breath, or enlarged lymph nodes. If you notice any of these symptoms, stop taking Dexilant and seek immediate medical attention, as these reactions can be life-threatening.
  • Common Side Effects in Adults:
    The most frequently reported side effects of Dexilant in adults include:

  • Diarrhea
  • Stomach pain
  • Nausea
  • Common cold
  • Vomiting
  • Gas
  • Common Side Effects in Children of Age 12 to 17 years:
    In adolescents, the most common side effects of Dexilant are:

    • Headache
    • Stomach pain
    • Diarrhea
    • Swelling in the mouth, nose, or throat

    Other Side Effects:
    Serious allergic reactions are rare but possible with Dexilant. Inform your doctor if you experience any of the following symptoms, as they may be indicative of an allergic reaction:

    • Rash
    • Swelling of the face
    • Tightness in the throat
    • Difficulty breathing

    Your doctor may discontinue Dexilant if you develop these symptoms.

    If you encounter any side effect that is bothersome or persists, be sure to discuss it with your healthcare provider. It’s crucial to weigh the potential benefits of Dexilant against these possible side effects and have a thorough conversation with your healthcare provider before starting or continuing this medication.

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