Xigduo XR (Dapagliflozin Propanediol Monohydrate / Metformin Hydrochloride)

Product Review

Xigduo XR
Dapagliflozin Propanediol Monohydrate, Metformin Hydrochloride

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Xigduo XR (Dapagliflozin Propanediol Monohydrate / Metformin Hydrochloride)

Dapagliflozin

Dapagliflozin is a prescription medication that belongs to a class of drugs called SGLT2 inhibitors. It is specifically designed for the treatment of type 2 diabetes in adults, and to reduce the risk of hospitalization in patients with heart failure. Dapagliflozin helps to lower blood sugar levels by promoting the excretion of excess glucose through urine. It is often used alongside a healthy diet and regular exercise to effectively manage blood sugar levels in patients with type 2 diabetes.

Why Choose Dapagliflozin?

Dapagliflozin works by inhibiting the sodium-glucose co-transporter 2 (SGLT2) protein, which is responsible for reabsorbing glucose in the kidneys. By blocking the action of SGLT2, the medication helps the kidneys to remove excess glucose from the body through urine. This process helps lower blood sugar levels and manage type 2 diabetes more effectively. The exact mechanism is heart failure is not well understood.

How to use Dapagliflozin?

Dapagliflozin is available in tablet form and should be taken orally once daily, typically in the morning, with or without food. The dosage of Dapagliflozin may vary depending on the patient’s medical condition, response to treatment, and other medications they may be taking. It is important to follow your healthcare provider’s recommendations and the instructions on the prescription label.

Important Safety Information about Dapagliflozin

Before using Dapagliflozin, inform your healthcare provider if you have any allergies, kidney problems, liver disease, dehydration, low blood pressure, or a history of urinary tract infections. Dapagliflozin may interact with other medications, so inform your healthcare provider of all prescription and non-prescription medications you are currently taking.

Dapagliflozin is not recommended for use during pregnancy or breastfeeding. Consult your healthcare provider for more information and guidance.

Fact Table of Dapagliflozin

Fact Fact Details
Product Name Dapagliflozin
Drug Class SGLT2 Inhibitors
Use Treatment of Type 2 Diabetes in adults
Mechanism of Action Inhibits SGLT2 protein, promoting the excretion of excess glucose through urine
Dosage Form Oral tablet
Dosage Frequency Once daily
Precautions Kidney problems, liver disease, dehydration, low blood pressure, history of urinary tract infections
Pregnancy & Nursing Not recommended
Drug Interactions May interact with other medications; inform the healthcare provider of all medications being taken

Common Side Effects of Dapagliflozin

As with any medication, Dapagliflozin may cause side effects. Some common side effects include:

  • Urinary tract infections
  • Yeast infections in women and men
  • Thirst
  • Increased urination
  • Dehydration

If you experience any serious side effects, such as signs of kidney problems, persistent nausea or vomiting, severe dizziness, or an allergic reaction, contact your healthcare provider immediately.

How Can You Buy Dapagliflozin?

You can order Dapagliflozin using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

Does Dapagliflozin work for weight loss?

Dapagliflozin, a medication used primarily for managing type 2 diabetes, has been associated with weight loss as a secondary effect. By inhibiting glucose reabsorption in the kidneys, dapagliflozin promotes the excretion of excess glucose through urine, resulting in a calorie deficit and potential weight reduction. However, it’s important to note that dapagliflozin is not specifically approved as a standalone weight loss treatment, and its effects on weight can vary among individuals. Consultation with a healthcare professional is recommended to determine the suitability and potential benefits of dapagliflozin for weight management.

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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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