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Prolia (Denosumab)
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This is a refrigerated product. A default $29.99 Express shipping fee is applied. It will be shipped out in a insulated styrofoam container with gel and ice packs inside. Parcels are shipped via Canada Post Express.
Prolia (Denosumab)
Prolia® is a prescription medication used to treat osteoporosis in postmenopausal women and men at high risk of fractures, those who have failed or are intolerant to other available osteoporosis therapy. Prolia® works by inhibiting the action of a protein involved in bone resorption, helping to increase bone mass and strength, thereby reducing the risk of fractures.
Why Choose Prolia (Denosumab)?
- Reduces the risk of vertebral, nonvertebral, and hip fractures in postmenopausal women with osteoporosis.
- Helps to increase bone mass in men with osteoporosis at high risk of fracture.
- Administered as a subcutaneous injection every six months, offering convenience compared to daily or weekly treatments.
How to Use Prolia (Denosumab)?
Prolia® is administered as a 60 mg/mL solution for subcutaneous injection by a healthcare professional every six months. It is crucial to continue regular follow-ups and adhere to the prescribed treatment schedule for optimal benefits.
Important Safety Information about Prolia
- Do not use Prolia® if you have low blood calcium (hypocalcemia) or are allergic to denosumab or any of its ingredients.
- Prolia® can cause serious side effects, including low blood calcium levels, severe infections, and severe skin reactions.
- Patients should take calcium and vitamin D as directed by their healthcare provider to prevent low blood calcium levels.
- Tell your doctor about any medical conditions, including kidney problems, or if you are taking any other medications.
Fact Table
| Facts | Detail |
| Generic Name | Denosumab |
| Brand Name | Prolia |
| Classification | Monoclonal antibody |
| FDA Approval Date | June 1, 2010 |
| Indications | Used for osteoporosis in postmenopausal women and men at high risk for fracture, certain cancer treatments causing bone loss, and glucocorticoid-induced osteoporosis. |
| Dosage Form | Subcutaneous injection |
| Strength | 60 mg/mL |
| Administration | Once every six months |
| Mechanism of Action | Inhibits RANKL, decreasing bone resorption and increasing bone mass and strength in osteoporosis and other bone disorders. |
| Common Side Effects | – Back pain – Pain in extremity – Musculoskeletal pain – Hypercholesterolemia – Cystitis |
| Serious Side Effects | – Osteonecrosis of the jaw – Atypical femoral fractures – Serious infections – Hypocalcemia |
| Contraindications | – Hypersensitivity to denosumab – Pre-existing hypocalcemia |
| Pregnancy Category | Category X (should not be used during pregnancy) |
| Storage Instructions | Store in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Keep the product in the original carton to protect it from light until the time of use. |
Common Side Effects
Like all medications, Prolia (Denosumab) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.
- Pain in the back, arms, and legs
- High cholesterol levels
- Muscle pain
- Bladder infection symptoms, such as burning during urination or frequent urination
If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.
How Can You Buy Prolia (Denosumab)?
You can order Prolia (Denosumab) using these methods on our website:
- Order Online
- Order by Phone
- Order by Fax
- Order your refills
Visit our How to order page.
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PharmaServe now offers you the option to make 4-interest-free payments by credit card once your order is confirmed using
Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care.
He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff.
He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications.
His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
Please call 1-800-258-0477 or email us if you have any questions or concerns.
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