Imitrex (Sumatriptan Succinate)

Sumatriptan Succinate

Sumatriptan Succinate



Imitrex (Sumatriptan Succinate)

Imitrex Prefilled Syringes contains sumatriptan, a medication used for the acute treatment of migraine attacks with or without aura in adults. Designed for rapid relief, these prefilled syringes offer a convenient, ready-to-use option to help manage the onset of migraine symptoms.

Why Choose Imitrex Prefilled Syringes (Sumatriptan)?


  • Fast Acting: Begins to relieve migraine pain within 10 to 15 minutes after injection.
  • Convenient: No need for measuring doses, ensuring quick and correct delivery every time.
  • Portable: Compact design makes it easy to carry in your purse or pocket for use anytime, anywhere.
  • Effective: Specifically targets serotonin receptors to reduce inflammation and constrict blood vessels, effectively alleviating pain and associated symptoms.
  • Direct Administration: Bypasses the digestive system, making it an ideal option for patients who experience nausea and vomiting during migraines.

How to Use Imitrex Prefilled Syringes (Sumatriptan)?


  • Check the Syringe: Ensure the solution is clear and colorless. Do not use if it is discolored or contains particles.
  • Prepare the Injection Site: Clean the injection site (usually thigh or upper arm) with an alcohol swab.
  • Remove Safety Cap: Pull off the syringe’s cap to reveal the needle.
  • Inject the Medication: Follow your doctor’s instructions to inject the medication subcutaneously (under the skin).
  • Dispose of the Syringe: Use a sharps container to dispose of the syringe safely.

Important Safety Information about Imitrex Prefilled Syringes


  • Imitrex should not be used to prevent migraines or cluster headaches; it is intended for acute symptoms only.
  • Avoid using if you have heart disease, circulation problems, or a history of heart attack or stroke.
  • Consult your doctor before use if you are pregnant, planning to become pregnant, or breastfeeding.
  • Do not take Imitrex within 24 hours before or after using another migraine headache medicine.
  • Inform your doctor of all medications you are currently taking to avoid potential interactions.

Fact Table for Imitrex Prefilled Syringes

Facts Details
Product Name Imitrex Prefilled Syringes
Active Ingredient Sumatriptan
Indications Used to treat migraine headaches with or without aura in adults.
How it Works Sumatriptan works by narrowing blood vessels around the brain and reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.
Administration Route Subcutaneous (under the skin)
Dosage Form Prefilled syringe
Strengths Available Typically available in 4 mg and 6 mg doses
Usage Instructions – Use only as directed by a healthcare provider – Inject subcutaneously at the onset of migraine symptoms – Follow the provided instructions for injection technique – Do not inject more than two doses in 24 hours.
Side Effects Pain or redness at the injection site, dizziness, tingling sensation, warm/hot sensation.
Storage Requirements Store between 2°C to 8°C (36°F to 46°F); do not freeze. Keep away from light.
FDA Approval Originally approved in 1992
Warnings and Precautions – Not for use in patients with certain cardiovascular diseases due to the risk of serious cardiac events – Not for use in the treatment of hemiplegic or basilar migraine – Use caution in patients with risk factors for vascular disease.
Interactions Avoid using with MAO inhibitors, other 5-HT1 agonists, or substances that increase blood pressure.
Pregnancy Category Category C (risk not ruled out)


Common Side Effects of Imitrex Prefilled Syringes

Like all medications, Imitrex Prefilled Syringes (Sumatriptan) can cause side effects, although not everybody gets them. Understanding these side effects can help you use this medication safely and effectively.

  • Injection Site Reactions
  • Nausea and Vomiting
  • Dizziness
  • Tiredness


If you experience any side effects, discuss them with your healthcare provider. They can offer advice and may adjust your treatment if necessary. Report any severe or unexpected side effects immediately.

How Can You Buy Imitrex Prefilled Syringes (Sumatriptan)?

You can order Imitrex Prefilled Syringes (Sumatriptan) using these methods on our website:

  1. Order Online
  2. Order by Phone
  3. Order by Fax
  4. Order your refills

Visit our How to order page.

Interest-Free Payments


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Dr. Conor Sheehy, PharmD, BCPS is a practicing clinical pharmacist that works in primary care. He supports other members of the healthcare team including physicians, mid-level providers, nurses, and other clinical staff. He also likes to use his drug knowledge to inform his patients and the public about the benefits and risks they can expect from their medications. His clinical specialties include: anticoagulation, diabetes management, and psychiatric care.
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Please note that due to government rules and regulations, orders may not exceed 3 months in supply.
Please call 1-800-258-0477 or email us if you have any questions or concerns.