Ocrevus

Frequently Asked Questions

1. What is Ocrevus used for?

   Ocrevus is primarily used to treat multiple sclerosis (MS). It is effective in both relapsing forms of MS, including relapsing-remitting MS and active secondary progressive disease, as well as primary progressive MS.

2. How does Ocrevus work?

   Ocrevus works by targeting a protein called CD20 on the surface of B cells, a type of white blood cell. It helps reduce inflammation and slows disease progression by destroying these cells, which are implicated in the damage caused by MS.

3. What are the most common side effects of Ocrevus?

   Common side effects include infusion reactions, infections (such as respiratory and skin infections), and a possible increase in the risk of certain cancers, including breast cancer. It’s important to monitor for signs of serious infections and report them to a healthcare provider.

4. How is Ocrevus administered?

   Ocrevus is given as an intravenous infusion. The first dose is divided into two infusions two weeks apart. Subsequent doses are given as a single infusion every six months.

5. What should I do if I miss a dose of Ocrevus?

   If you miss a dose, contact your healthcare provider to reschedule it as soon as possible. It is important not to wait until the next scheduled dose. Future infusions should be spaced six months apart.

6. Can Ocrevus affect pregnancy and breastfeeding?

   Ocrevus may pose risks during pregnancy and breastfeeding. Women should use effective contraception during treatment and for six months after the last dose. It is not known if Ocrevus is present in breast milk.

7. What should I tell my healthcare provider before starting Ocrevus?

   Inform your healthcare provider about any infections, history of hepatitis B, recent vaccinations, and any other medications you are taking, especially those that affect the immune system.

8. How long does it take for Ocrevus to work?

   Some effects, such as reduced relapse rates, can be seen within 12 weeks, but full benefits may take six months or longer to manifest.

9. Can I receive vaccinations while on Ocrevus?

   Live vaccines should be avoided during treatment. Non-live vaccines should ideally be given at least two weeks before starting Ocrevus.

10. Is Ocrevus a form of chemotherapy?

    No, Ocrevus is not chemotherapy. It is a monoclonal antibody that targets specific proteins on B cells and is used to treat MS by modulating the immune system.